SHP099 hydrochloride
CAS No. 1801747-11-4
SHP099 hydrochloride ( —— )
产品货号. M17381 CAS No. 1801747-11-4
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥741 | 有现货 |
|
10MG | ¥1358 | 有现货 |
|
50MG | ¥4586 | 有现货 |
|
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称SHP099 hydrochloride
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor.
-
产品描述SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor.
-
同义词——
-
通路Endocrinology/Hormones
-
靶点5-HT Receptor
-
受体SHP-2
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number1801747-11-4
-
分子量388.72
-
分子式C16H20Cl3N5
-
纯度98%
-
溶解度Methanol : 15 mg/mL 38.59 mM; DMSO : 4.1 mg/mL 10.55 mM; H2O : ≥ 2.5 mg/mL 6.43 mM
-
SMILESNc1nc(N2CCC(C)(N)CC2)cnc1c1cccc(Cl)c1Cl.Cl
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Chen YN, et al. Nature. 2016 Jul 7;535(7610):148-52.
产品手册
关联产品
-
DSP-1053
DSP-1053 is a novel potent serotonin reuptake (SERT) inhibitor with 5-HT1A partial agonistic activity that binds to human serotonin transporter and 5-HT1A receptor with Ki of 1.02 and 5.05 nM, respectively.
-
GR-127935
GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor.
-
Cannabigerol
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.